Article
Inflammation and oxidative stress in carcinogenesis.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) - 1 Jan 1991
Cerutti P A, Trump B F
Abstract excerpt
Oxidants, which are generated by multiple pathways in mammalian organisms, may be natural carcinogens and contribute to several stages of malignant transformation. Active oxygen released by inflammatory phagocytes and more stable "clastogenic factors" can induce mutations and chromosomal aberrati...
Topics
- Animals
- DNA Damage
- Gene Expression
- Humans
- Inflammation
- Mutation
- Neoplasms
- Oxidation-Reduction
- Oxygen
- Proto-Oncogene Mas