A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings.

doi:10.1128/jcm.35.3.791-795.1997

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Article

A general primer GP5+/GP6(+)-mediated PCR-enzyme immunoassay method for rapid detection of 14 high-risk and 6 low-risk human papillomavirus genotypes in cervical scrapings.

Journal of clinical microbiology - 1 Mar 1997

Jacobs M V, Snijders P J, van den Brule A J, Helmerhorst T J, Meijer C J, Walboomers J M

Abstract excerpt

Two cocktails of digoxigenin-labeled human papillomavirus (HPV) type-specific oligonucleotide probes and an enzyme immunoassay (EIA) were used as a basis to developed a group-specific detection method for 14 high-risk (types 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, and 68) and 6 low-ri...

Topics

Base Sequence
Cervix Uteri
DNA Primers
Female
Genotype
Humans
Immunoenzyme Techniques
Mass Screening
Papillomaviridae
Papillomavirus Infections
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Sensitivity and Specificity

Tumor Virus Infections

Uterine Cervical Diseases

Uterine Cervical Neoplasms

Virology

Source

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Identifiers

PMID: 9041439
DOI: 10.1128/jcm.35.3.791-795.1997
PMCID: PMC229677

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9041439-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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