Article
Effects of malnutrition on expression and activity of lactase in children.
Gastroenterology - 1 Mar 1997
Nichols B L, Dudley M A, Nichols V N, Putman M, Avery S E, Fraley J K, Quaroni A, Shiner M, Carrazza F R
Abstract excerpt
BACKGROUND & AIMS: Many malnourished infants have reduced lactase specific activity in the small intestine. The aim of this study was to test the hypothesis that the hypolactasia of malnourished infants results from transcriptional suppression of lactase expression. METHODS: Biopsy specimens were studied from two groups of infants: 29 with malnutrition and 10 normally nourished controls with normal morphology and...
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