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Article

Predisposition to cancer in children and adolescents.

The Lancet. Child & adolescent health - 1 Feb 2021

Kratz Christian P, Jongmans Marjolijn C, Cavé Hélène, Wimmer Katharina, Behjati Sam, Guerrini-Rousseau Lea, Milde Till, Pajtler Kristian W, Golmard Lisa, Gauthier-Villars Marion, Jewell Rosalyn, Duncan Catriona, Maher Eamonn R, Brugieres Laurence, Pritchard-Jones Kathy, Bourdeaut Franck

Abstract excerpt

Childhood malignancies are rarely related to known environmental exposures, and it has become increasingly evident that inherited genetic factors play a substantial causal role. Large-scale sequencing studies have shown that approximately 10% of children with cancer have an underlying cancer predisposition syndrome. The number of recognised cancer predisposition syndromes and cancer predisposition genes are...

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Adolescent
Child
Childhood Cancer Survivors' Quality of Life
Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Testing

Medical Oncology

Risk Assessment

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PMID: 33484663
DOI: 10.1016/S2352-4642(20)30275-3

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