Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Predisposition to cancer in children and adolescents.

The Lancet. Child & adolescent health - 1 Feb 2021

Kratz Christian P, Jongmans Marjolijn C, Cavé Hélène, Wimmer Katharina, Behjati Sam, Guerrini-Rousseau Lea, Milde Till, Pajtler Kristian W, Golmard Lisa, Gauthier-Villars Marion, Jewell Rosalyn, Duncan Catriona, Maher Eamonn R, Brugieres Laurence, Pritchard-Jones Kathy, Bourdeaut Franck

Abstract excerpt

Childhood malignancies are rarely related to known environmental exposures, and it has become increasingly evident that inherited genetic factors play a substantial causal role. Large-scale sequencing studies have shown that approximately 10% of children with cancer have an underlying cancer predisposition syndrome. The number of recognised cancer predisposition syndromes and cancer predisposition genes are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Childhood Cancer Survivors' Quality of Life

Share to Genetic Predisposition to Disease

Share to Genetic Testing

Share to Medical Oncology

Share to Neoplasms

Share to Risk Assessment

Source

Identifiers

PMID: 33484663
DOI: 10.1016/S2352-4642(20)30275-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Predisposition to cancer in children and adolescents.PMID 33484663Read ↗

Genetic predisposition to cancers in children and adolescents.Semantic proximity Read ↗

Genetic causes of cancer predisposition in children and adolescents.Semantic proximity Read ↗

Childhood cancer predisposition study: a prospective registry and biorepository protocol.Semantic proximity Read ↗

Childhood cancer predisposition syndromes-A concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric Oncology and Hematology.Semantic proximity Read ↗

Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review.Semantic proximity Read ↗

Inherited cancer in children: practical/ethical problems and challenges.Semantic proximity Read ↗

Genetic predisposition to cancer: Surveillance and intervention.Semantic proximity Read ↗

[Germ line mutations causing paediatric cancer predisposition syndromes are common in children and adolescents with cancer].Semantic proximity Read ↗

Cancer Predisposition Syndromes in Children: Who, How and When Should Genetic Studies Be Considered?Semantic proximity Read ↗

The genetic era of childhood cancer: Identification of high-risk patients and germline sequencing approaches.Semantic proximity Read ↗

[Genetic predisposition in children cancers in 2011].Semantic proximity Read ↗

Cancer Predisposition Syndromes in Children: Who, How, and When Should Genetic Studies Be Considered?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.