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Article

Association of human papillomavirus type 16 integration in the <i>E2</i> gene with poor disease‐free survival from cervical cancer

20 Feb 1997

Abstract excerpt

To determine the clinical relevance of human papillomavirus (HPV) integration and E2 function suggested by in vitro studies, we investigated 50 patients with HPV 16-positive primary cervical carcinoma (stage Ib-IV) diagnosed and treated at one institution. The physical state of HPV was determined by colorimetric in situ hybridization and was not found to vary by stage. Overall, 62% of tumors had integrated HPV,...

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Identifiers

PMID: 9036869
DOI: 10.1002/(sici)1097-0215(19970220)74:1<50::aid-ijc9>3.0.co;2-#

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Association of human papillomavirus type 16 integration in the <i>E2</i> gene with poor disease‐free survival from cervical cancerPMID 9036869Read ↗

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