Article
Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm
1 Feb 1991
Abstract excerpt
The integration of human papillomavirus (HPV) DNA into the human genome has been generally accepted as a characteristic of malignant lesions. To gain a better understanding of this phenomenon, genomic DNA from 181 cervical biopsy specimens was isolated and analyzed for HPV type and physical state of the HPV genome. These specimens represented the full spectrum of cervical disease, from condyloma to invasive...
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