The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad.

doi:10.1128/JVI.71.3.2425-2435.1997

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Article

The transneuronal spread phenotype of herpes simplex virus type 1 infection of the mouse hind footpad.

Journal of virology - 1 Mar 1997

Engel J P, Madigan T C, Peterson G M

Abstract excerpt

The mouse hind footpad inoculation model has served as a standard laboratory system for the study of the neuropathogenesis of herpes simplex virus type 1 (HSV-1) infection. The temporal and spatial distribution of viral antigen, known as the transneuronal spread phenotype, has not previously been...

Topics

Animals
Antigens, Viral
Brain
Brain Stem
Disease Models, Animal
Ganglia, Spinal
Herpes Simplex
Herpesvirus 1, Human
Hindlimb
Humans
Male
Mice
Neurons
Phenotype
Spinal Cord
Spinal Nerve Roots

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