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Article

A boy with X-linked hyper-IgM syndrome and natural killer cell deficiency.

Clinical and experimental immunology - 1 Feb 1997

Ostenstad B, Giliani S, Mellbye O J, Nilsen B R, Abrahamsen T

Abstract excerpt

We present a boy with hyper-IgM syndrome with a previously not reported mutation in the CD40 ligand gene. He also had a concomitant natural killer (NK) cell deficiency. He had no CD56+ or CD16+ cells and no NK activity as determined in 4 h chromium release cytotoxicity assay. After 5 days in culture with IL-2-containing medium, however, his peripheral blood mononuclear cells lysed both NK-sensitive and...

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Identifiers

PMID: 9030857
DOI: 10.1111/j.1365-2249.1997.284-ce1174.x
PMCID: PMC1904570

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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