Changes in the cellular composition of Candida albicans resistant to miconazole.

Article

Changes in the cellular composition of Candida albicans resistant to miconazole.

Indian journal of biochemistry & biophysics - 1 Oct 1996

Sharma S, Khuller G K

Abstract excerpt

Biochemical changes that accompany acquisition of miconazole resistance in a single step mutant of C. albicans 3153 were analyzed. Experiments show that resistance to this drug was associated with decrease in total lipids, phospholipids and sterol content. Fluorescence polarization studies with 1...

Topics

Antifungal Agents
Candida albicans
Drug Resistance, Microbial
Lipid Metabolism
Membrane Fluidity
Miconazole
Mutation
Proline

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