Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hb Puttelange [beta 140(H19)Ala-->Val] in an Italian man with polycythemia.

Hemoglobin - 1 Jan 1997

Galanello R, Paleari R, Perseu L, Barella S, Maccioni L, Cao A, Mulas G, Cocco E, Mosca A

Abstract excerpt

Hb Puttelange [beta 140(H18)Ala-->Val] was found in a 51-year-old Italian man who had mild polycythemia. The variant eluted from ion exchange high performance liquid chromatography at a position between Hb A and Hb A2. It comprised approximately 34% of the total hemoglobin, was weakly unstable and exhibited an increased oxygen affinity. Amplification of the beta-globin exons and nucleotide sequencing revealed a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Genotype
Share to Hemoglobins, Abnormal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oxygen

Share to Thalassemia

Source

Identifiers

PMID: 9028820
DOI: 10.3109/03630269708997507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hb Puttelange [beta 140(H19)Ala-->Val] in an Italian man with polycythemia.PMID 9028820Read ↗

Germline mosaicism for an alanine to valine substitution at residue beta 140 in hemoglobin Puttelange, a new variant with high oxygen affinity.Semantic proximity Read ↗

Hb Rainier [beta145(HC2)Tyr-->Cys] in Italy. Characterization of the amino acid substitution and the DNA mutation.Semantic proximity Read ↗

Haemoglobin Pierre-Benite--a high affinity variant associated with relative polycythaemia.Semantic proximity Read ↗

Hb F-Avellino [(G)γ41(C7)Phe → Leu; HBG2: c.124 T > C]: A New Hemoglobin Variant Observed In A Healthy Newborn.Semantic proximity Read ↗

Hb Belfast [beta15(A12)Trp-->Arg]: definition of the clinical and hematological phenotype.Semantic proximity Read ↗

Hb Trollhättan [beta 20(B2)Val-->Glu]--a new haemoglobin variant with increased oxygen affinity causing erythrocytosis.Semantic proximity Read ↗

Two new alpha chain variants: Hb Boghé [alpha58(E7)His-->Gln, alpha2], a variant on the distal histidine, and Hb CHarolles [alpha103(G10)His-Tyr, alpha1].Semantic proximity Read ↗

Hb Montfermeil [beta 130(H8) Tyr-->Cys]: suggests a key role for the interaction between helix A and H in oxygen affinity of the hemoglobin molecule.Semantic proximity Read ↗

Hb Schlierbach or beta108(G10)Asn-->Ile: a new variant with low oxygen affinity detected in a Swiss family.Semantic proximity Read ↗

Hb Geelong [beta 139(H17)Asn----Asp].Semantic proximity Read ↗

Novel haemoglobin mutation (α127Lys→Glu) increases oxygen affinity and has a minor effect on haptoglobin binding.Semantic proximity Read ↗

A new unstable hemoglobin variant with low oxygen affinity: Hb Ilmenau [beta41 (C7)Phe-->Cys].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.