Article
Hb Geelong [beta 139(H17)Asn----Asp].
Hemoglobin - 1 Jan 1991
Como P F, Hocking D R, Swinton G W, Trent R J, Holland R A, Tibben E A, Wilkinson T, Kronenberg H
Abstract excerpt
Hb Geelong [beta 139(H17)Asn----Asp] was detected in a German woman of Polish-Russian descent. It is an unstable variant which appears to increase the severity of a beta (+)-thalassemic phenotype in the propositus. The electrophoretic properties of Hb A and Hb Geelong are similar on cellulose ace...
Topics
- 2,3-Diphosphoglycerate
- Adult
- Amino Acid Sequence
- Diphosphoglyceric Acids
- Female
- Globins
- Hemoglobinopathies
- Hemoglobins, Abnormal
- Humans
- Molecular Sequence Data
- Oxygen
- Phenotype
- Thalassemia