Hb Trollhättan [beta 20(B2)Val-->Glu]--a new haemoglobin variant with increased oxygen affinity causing erythrocytosis.

Article

Hb Trollhättan [beta 20(B2)Val-->Glu]--a new haemoglobin variant with increased oxygen affinity causing erythrocytosis.

European journal of haematology - 1 Jul 1994

Landin B, Berglund S, Lindoff B

Abstract excerpt

Erythrocytosis is sometimes caused by the presence of haemoglobin (Hb) variants with increased oxygen affinity. Here we describe a beta-globin variant found by isoelectric focusing (IEF) of Hb from a 23-year-old Swedish male with moderate erythrocytosis. Amplification of DNA corresponding to the...

Topics

Adult
Amino Acid Sequence
Base Sequence
Codon
DNA
Globins
Glutamates
Glutamic Acid
Haplotypes
Hemoglobins, Abnormal
Humans
Male
Molecular Sequence Data
Mutation
Oxygen
Polycythemia
Sweden
Valine

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