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Article

The effect of eight V2 vasopressin receptor mutations on stimulation of adenylyl cyclase and binding to vasopressin.

The Journal of biological chemistry - 16 Dec 1994

Pan Y, Wilson P, Gitschier J

Abstract excerpt

We previously identified six V2 vasopressin receptor mutations in five unrelated nephrogenic diabetes insipidus (NDI) families. In order to elucidate the effect of these mutations on the function of the V2 vasopressin receptor, we introduced these six and two additional, naturally occurring mutat...

Topics

Adenylyl Cyclases
Amino Acid Sequence
Diabetes Insipidus
Enzyme Activation
Epitopes
Humans
Immunologic Techniques
In Vitro Techniques
Molecular Sequence Data
Mutation
Receptors, Vasopressin
Signal Transduction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Transfection

Vasopressins

Source

Identifiers

PMID: 7527400

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7527400-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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