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Article

Expression studies of two vasopressin V2 receptor gene mutations, R202C and 804insG, in nephrogenic diabetes insipidus.

Kidney international - 1 Aug 1995

Tsukaguchi H, Matsubara H, Inada M

Abstract excerpt

Nephrogenic diabetes insipidus (NDI) is a rare X-linked disorder associated with renal tubule resistance to arginine vasopressin (AVP). To understand the mechanisms of AVP resistance underlying this disorder, we have analyzed the vasopressin V2 receptor gene in two unrelated Japanese kindreds with NDI and expressed the mutants to characterize their functional properties. Direct sequencing revealed two V2 receptor...

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Source

Identifiers

PMID: 7564126
DOI: 10.1038/ki.1995.327

Genes

AVP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Expression studies of two vasopressin V2 receptor gene mutations, R202C and 804insG, in nephrogenic diabetes insipidus.PMID 7564126Read ↗

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Functional studies of twelve mutant V2 vasopressin receptors related to nephrogenic diabetes insipidus: molecular basis of a mild clinical phenotype.Semantic proximity Read ↗

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The effect of eight V2 vasopressin receptor mutations on stimulation of adenylyl cyclase and binding to vasopressin.Semantic proximity Read ↗

Functional characterization of five V2 vasopressin receptor gene mutations.Semantic proximity Read ↗

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The property of a novel v2 receptor mutant in a patient with nephrogenic diabetes insipidus.Semantic proximity Read ↗

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Functional characterization of a loss-of-function mutant I324M of arginine vasopressin receptor 2 in X-linked nephrogenic diabetes insipidus.Semantic proximity Read ↗

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