AVPR2 variants and V2 vasopressin receptor function in nephrogenic diabetes insipidus.

doi:10.1046/j.1523-1755.1998.00214.x

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Article

AVPR2 variants and V2 vasopressin receptor function in nephrogenic diabetes insipidus.

Kidney international - 1 Dec 1998

Wildin R S, Cogdell D E, Valadez V

Abstract excerpt

BACKGROUND: The AVPR2 gene encodes the type 2 vasopressin receptor, a member of the vasopressin/oxytocin receptor subfamily of G protein-coupled receptors. Disruption of AVPR2 causes X-linked congenital nephrogenic diabetes insipidus (NDI), yet the functional significance of most gene sequence va...

Topics

Amino Acid Sequence
Animals
Conserved Sequence
Diabetes Insipidus, Nephrogenic
Female
Genetic Variation
Humans
Infant
Infant, Newborn
Male
Mutation
Oxytocin
Receptors, Cell Surface
Receptors, Oxytocin
Receptors, Vasopressin

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