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Article

HIV-1 induces cytotoxic T lymphocytes in the cervix of infected women.

The Journal of experimental medicine - 20 Jan 1997

Musey L, Hu Y, Eckert L, Christensen M, Karchmer T, McElrath M J

Abstract excerpt

Although T lymphocytes are present in the genital mucosa, their function in sexually transmitted diseases is unproven. To determine if cervical T cells mediate HIV-specific cytolysis, mononuclear cells in cytobrush specimens from HIV-1-infected women were stimulated in vitro with antigen. Resultant cell lines lysed autologous targets expressing HIV-1 proteins in 12/19 (63%) subjects, and these responses were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 9016878
DOI: 10.1084/jem.185.2.293
PMCID: PMC2196121

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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