Article
Regulation of Transcriptional Activity during the First and Second Cell Cycles in the Preimplantation Mouse Embryo
1 Jan 1997
Abstract excerpt
Transcription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determined by monitoring the incorporation of BrUTP by plasma membrane-permeabilized embryos. Incorporation is observed starting by mid-S phase in the 1-cell embryo and increases progressively; the amount of incorporation by the 1-cell embryo in G2 is about 20% that of the 2-cell embryo in G2. Incorporation by the male pronucleus...
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