Molecular characterization of virus-specific RNA produced in the brains of flavivirus-susceptible and -resistant mice after challenge with Murray Valley encephalitis virus.

Abstract excerpt

Natural resistance to flaviviruses in mice is controlled by a single genetic locus, FIv, on chromosome 5. Although the mechanism of this resistance is not fully understood, it is believed to operate at the level of virus replication rather than the immune response. It has been hypothesized that enhanced production of viral defective interfering (DI) particles is responsible for a substantial reduction in the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to HIV Research and Treatment
• Share to Mosquito-borne diseases and control
• Share to Viral Infections and Vectors