Article
Tumour suppressor genes, immunology and local manifestations of neurofibromatosis phenotypes.
Panminerva medica - 1 Sept 1996
Gerosa P L, Spinelli M, Iannarelli S, Giussani G, Canepari C, Fontana A, Vai C, Bizzozero L
Abstract excerpt
Research on Neurofibromatosis (NF) has been directed at understanding what determines disease quiescence, exacerbation, and the possible malignant evolution. Studies on NF have examined the role of genetic oncosuppression in the evolution of the defence against the non-self. Paraffin fixed specimens of benign and malignant neoplasia, occurring in patients with NF1 and NF2, were tested for the presence of p53: a...
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