Article
In vivo spontaneous neuronal to neuroendocrine lineage conversion in a subset of neuroblastomas.
The American journal of pathology - 1 Jan 1997
Gestblom C, Hoehner J C, Hedborg F, Sandstedt B, Påhlman S
Abstract excerpt
Neuroblastoma is an embryonal tumor derived from the sympathetic nervous system. Although all neuroblastomas have a neuronal character, a subset of tumors also show evidence of extra-adrenal neuroendocrine differentiation in discrete cell layers. A characterization of the cells of the developing...
Topics
- Cell Differentiation
- Child, Preschool
- Fetus
- Ganglioneuroma
- Humans
- Infant
- Infant, Newborn
- Neuroblastoma
- Neuronal Plasticity
- Neurons
- Neurosecretory Systems
- Phenotype
- Sympathetic Nervous System