Article
[Gene therapy in oncology: applications to lung cancer].
Revue des maladies respiratoires - 1 Oct 1996
Chapiro J, Palma M D, Mignot L, Lemonnier M P, Beaumelou E, Coulet F, Misset J L, Jasmin C
Abstract excerpt
Gene therapy defines a new therapeutic avenue whose site of action is at the level of the gene itself; viral vectors (adenovirus, retrovirus, herpes virus) or non-viral (liposomes, plasmids) enable the transfer of a fraction of DNA (transgenic) to the target itself. In this review, we present recently acquired data on the mechanisms of oncogenesis and anti-tumor immunity which have enabled the application of...
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