Article
Molecular analysis of DLA-DRBB1 polymorphism.
Tissue antigens - 1 Nov 1996
Wagner J L, Burnett R C, Works J D, Storb R
Abstract excerpt
The polymorphism of the canine major histocompatibility complex class II DRB gene, DRBB1, was analyzed. Exon 2 that encodes the polymorphic beta 1 domain was amplified by the polymerase chain reaction (PCR). The PCR product from 250 dogs was cloned and sequenced. Eighteen alleles were identified. Most of the variation in amino acid composition occurred at positions in the peptide binding site. Inheritance of...
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