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Article

Packaging signals in alphaviruses

1 Jan 1997

Abstract excerpt

Alphaviruses synthesize large amounts of both genomic and subgenomic RNA in infected cells, but usually only the genomic RNA is packaged. This implies the existence of an encapsidation or packaging signal which would be responsible for selectivity. Previously, we had identified a region of the Sindbis virus genome that interacts specifically with the viral capsid protein. This 132-nucleotide (nt) fragment lies...

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PMID: 8985344
DOI: 10.1128/jvi.71.1.248-258.1997

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