Antigenicity, pathogenicity, and immunogenicity of small and large plaque infectious bursal disease virus clones.

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Article

Antigenicity, pathogenicity, and immunogenicity of small and large plaque infectious bursal disease virus clones.

Avian diseases - 1 Jan 2000

Hassan M K, Nielsen C K, Ward L A, Jackwood D J, Saif Y M

Abstract excerpt

A serotype 1 variant strain of infectious bursal disease virus designated IN was passaged 40 times in BGM-70 cell line. A small plaque (SP) clone and a large plaque (LP) clone were then isolated and plaque purified four times. The SP and LP viruses formed circular plaques about 0.5 mm and 6.0 mm...

Topics

Animals
Antibodies, Viral
Birnaviridae Infections
Cell Line
Chickens
DNA, Viral
Enzyme-Linked Immunosorbent Assay
Infectious bursal disease virus
Phenotype
Polymerase Chain Reaction
Poultry Diseases
Spleen
Vaccines, Inactivated
Viral Plaque Assay
Viral Vaccines

Source

Open in PubMed

Identifiers

PMID: 8980814

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8980814-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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