Article
Genetic mapping of the determinants of plaque morphology of coxsackievirus B4.
Archives of virology - 1 Jan 1995
Ramsingh A I, Caggana M, Ronstrom S
Abstract excerpt
The genetic determinants of plaque size of two variants of coxsackie-virus B4, CB4-P and CB4-V, were identified using a panel of recombinant, chimeric viruses. When grown in monkey kidney cells, CB4-V yielded large plaques with an average size of 1.0 cm while CB4-P yielded small plaques with an average size of 0.4 cm. Two genetic domains, the 5' untranslated region and the VP4 gene sequence, independently...
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