Article
beta-Amyloid protein precursor in Microcebus murinus: genotyping and brain localization.
Neurobiology of disease - 1 Jan 1996
Silhol S, Calenda A, Jallageas V, Mestre-Frances N, Bellis M, Bons N
Abstract excerpt
Senile plaques characterized by beta-amyloid protein (A beta) deposits around dystrophic neurites and glial cells are more abundant in the cerebral cortical parenchyma of Alzheimer's disease (AD) patients than in the aged population. Four different mutations in the amyloid precursor protein (APP) gene have been directly involved in a few cases of familial AD with early onset (before 60 years). Previous studies...
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