Article
[Cytogenetic abnormalities, genetic alterations, and applications for genetic diagnosis in breast cancer].
Nihon rinsho. Japanese journal of clinical medicine - 1 Dec 1996
Tsukamoto K, Emi M, Nakamura Y
Abstract excerpt
The etiology of breast cancer involves a complex interplay of exogenous and endogenous factors, including genetic factors. The identification of oncogenes, tumor suppressor genes and human mismatch repair genes has helped to refine the characterization of breast carcinogenesis. The major types of genetic alterations in breast cancer are amplification of protooncogenes (ERBB2 and MYC) and DNA from chromosome band...
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