Article
[Molecular alterations in breast cancer: clinical implications and new analytical tools].
La Revue de medecine interne - 1 Jun 2005
Gonçalves A, Viens P, Sobol H, Maraninchi D, Bertucci F
Abstract excerpt
PURPOSE: Breast cancer is a complex and heterogeneous disease resulting from various molecular alterations, the identification of which should have profound impact on the management of patients. CURRENT KNOWLEDGE AND KEY POINTS: The discovery of germline mutations within breast cancer susceptibility genes, such as BRCA1 and BRCA2, which are associated with a major risk of breast cancer during lifetime, has...
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