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Article

Infection of human hepatocyte cell lines with hepatitis C virus in vitro.

Journal of gastroenterology and hepatology - 1 Jan 2000

Tagawa M, Kato N, Yokosuka O, Ishikawa T, Ohto M, Omata M

Abstract excerpt

Hepatocyte related cell lines, namely human embryonic hepatocyte cell line (WRL68) and hepatoblastoma cell line (Hep G2), were tested for their ability to support hepatitis C virus (HCV) replication in vitro. The replicative intermediate of the minus strand HCV RNA was newly transcribed from the inoculated virus, and was stable in WRL68 cells over a period of 62 days. HCV RNA detected in the culture medium at 62...

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Identifiers

PMID: 8963027
DOI: 10.1111/j.1440-1746.1995.tb01341.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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