Article
Outline structure of the human L1 cell adhesion molecule and the sites where mutations cause neurological disorders.
The EMBO journal - 15 Nov 1996
Bateman A, Jouet M, MacFarlane J, Du J S, Kenwrick S, Chothia C
Abstract excerpt
The L1 cell adhesion molecule has six domains homologous to members of the immunoglobulin superfamily and five homologous to fibronectin type III domains. We determined the outline structure of the L1 domains by showing that they have, at the key sites that determine conformation, residues similar to those in proteins of known structure. The outline structure describes the relative positions of residues, the...
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