Article
Clinical and biochemical abnormalities in people heterozygous for hemochromatosis.
The New England journal of medicine - 12 Dec 1996
Bulaj Z J, Griffen L M, Jorde L B, Edwards C Q, Kushner J P
Abstract excerpt
BACKGROUND: Ten percent of whites are heterozygous for the HLA-linked hemochromatosis mutation. We performed a cross-sectional analysis of 1058 genotyped heterozygotes to define the effects of age and sex on the phenotype. METHODS: The heterozygous genotype was assigned to 505 male and 553 female...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Biopsy
- Child
- Child, Preschool
- Cross-Sectional Studies
- Female
- Ferritins
- Hemochromatosis
- Heterozygote
- Histocompatibility Testing
- Humans
- Infant
- Iron
- Liver