Article
[Characterization of the MCC gene product].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 1996
Matsumine A
Abstract excerpt
MCC is a gene located within human chromosome band 5q21 that shows somatically acquired mutations in colorectal cancer. Here we report the identification, tissue specific distribution, subcellular localization, and growth regulating activity of MCC protein. Immunohistochemical analysis of MCC pro...
Topics
- Animals
- Brain
- Cell Cycle
- Colonic Neoplasms
- Genes, MCC
- Humans
- Intestinal Mucosa
- Mice
- Mutation
- Proteins
- Signal Transduction
- Tumor Suppressor Proteins
