[Characterization of the MCC gene product].

Abstract excerpt

MCC is a gene located within human chromosome band 5q21 that shows somatically acquired mutations in colorectal cancer. Here we report the identification, tissue specific distribution, subcellular localization, and growth regulating activity of MCC protein. Immunohistochemical analysis of MCC protein in various tissues of mouse revealed heavy cytoplasmic staining of brain neuronal cells and intestinal epithelial...

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