Article
Switches in the expression and function of PACAP and VIP receptors during phenotypic interconversion in human neuroblastoma cells.
Neuropeptides - 1 Aug 1996
Lelièvre V, Becq-Giraudon L, Meunier A C, Muller J M
Abstract excerpt
Clonal human neuroblastoma cells SH-IN undergo a very conspicuous phenotypic change in culture. Large substrate-adherent cells with a slow growth rate give rise to small cells emerging in focal aggregates and growing to high cell densities. This is accompanied by a dramatic switch in the expression of receptors for the structurally related neuropeptides VIP (vasoactive intestinal polypeptide) and PACAP (pituitary...
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