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Article

Inactivation of a Novel Neuropeptide Y/Peptide YY Receptor Gene in Primate Species

1 Nov 1996

Abstract excerpt

Neuropeptide Y (NPY), peptide YY (PYY), and pancreatic polypeptide (PP) belong to a family of structurally related peptides which have numerous functions in both neural and endocrine signaling. By homology screening, we cloned a novel gene sharing the highest homology with the NPY Y1 receptor gene from humans, rabbits, and several other species. This novel gene of rabbit encodes a functional NPY/PYY receptor,...

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PMID: 8910290
DOI: 10.1074/jbc.271.44.27217

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