Article
Chlamydia trachomatis major outer membrane protein (MOMP) epitopes that activate HLA class II-restricted T cells from infected humans.
Journal of immunology (Baltimore, Md. : 1950) - 15 Nov 1996
Ortiz L, Demick K P, Petersen J W, Polka M, Rudersdorf R A, Van der Pol B, Jones R, Angevine M, DeMars R
Abstract excerpt
We localized peptide epitopes within the Chlamydia trachomatis (Ct) major outer membrane protein (MOMP) that activate human T cells. T-MOMP' cells were prepared by culturing PBL from 38 humans who had Ct infections in the presence of Ct serovar E MOMP. Some epitopes were first localized by quantifying proliferative responses of T-MOMP' cells to overlapping MOMP segments (sixths) that were produced in Escherichia...
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