Article
Determination of neutralizing epitopes in variable domains I and IV of the major outer-membrane protein from Chlamydia trachomatis serovar K.
Microbiology (Reading, England) - 1 Sept 1994
Villeneuve A, Brossay L, Paradis G, Hébert J
Abstract excerpt
Chlamydia trachomatis is a leading cause of sexually transmitted diseases and a number of strategies have been developed to produce vaccines to prevent its transmission. The purpose of this study was to map the neutralizing epitopes of C. trachomatis major outer-membrane protein (MOMP) serovar K by using anti-MOMP antibodies and synthetic peptides. Seven anti-MOMP monoclonal antibodies and three polyclonal...
Topics
- Amino Acid Sequence
- Antibody Specificity
- Antigens, Bacterial
- Bacterial Outer Membrane Proteins
- Chlamydia trachomatis
- Epitopes
- Genetic Variation
- Molecular Sequence Data
- Neutralization Tests
- Peptide Mapping