Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse.

doi:10.1016/0006-8993(96)00892-x

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Article

Impairment of the nitric oxide/cyclic GMP pathway in cerebellar slices prepared from the hph-1 mouse.

Brain research - 30 Sept 1996

Brand M P, Briddon A, Land J M, Clark J B, Heales S J

Abstract excerpt

In this study, the effect of tetrahydrobiopterin deficiency on the nitric oxide/cGMP pathway has been investigated in cerebellar slices derived from the hph-1 mouse. This animal displays a partial deficiency of tetrahydrobiopterin. Basal levels of cGMP were significantly reduced (-29.5%) in the h...

Topics

6-Cyano-7-nitroquinoxaline-2,3-dione
Animals
Antioxidants
Biopterins
Cerebellum
Cyclic GMP
Enzyme Inhibitors
Excitatory Amino Acid Agonists
Excitatory Amino Acid Antagonists
Glutathione
Kainic Acid
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred C57BL

Mice, Inbred CBA

Mice, Mutant Strains

Mutation

Nitric Oxide

Nitroarginine

Source

Open in PubMed

Identifiers

PMID: 8905183
DOI: 10.1016/0006-8993(96)00892-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8905183-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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