Article
Frequency distribution of XbaIG > T and HaeIIIT > C GLUT1 polymorphisms among different Brazilian ethnic groups.
Molecular biology reports - 1 Jan 2010
Costa G C S, Alcantara L C J, Azevedo R, Muricy G, Kashima S H, Covas D T, Galvão-Castro B, Gadelha S R
Abstract excerpt
GLUT is the major glucose transporter in mammalian cells. Single nucleotide polymorphisms (SNP) at GLUT1 promoter and regulatory regions have been associated to the risk of developing nephropathy in different type 1 and type 2 diabetic populations. It has been demonstrated that differences in allelic and genotypic frequencies of GLUT1 gene (SLC2A1) polymorphisms occur among different populations. Therefore,...
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