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Article

Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures.

Biochemistry - 29 Oct 1996

Mazumder A, Neamati N, Ojwang J O, Sunder S, Rando R F, Pommier Y

Abstract excerpt

An oligonucleotide (T30177) composed entirely of deoxyguanosine and thymidine has previously been shown to fold upon itself in the presence of potassium into a highly stable four-stranded DNA structure containing two stacked deoxyguanosine quartets (G4s). T30177 also protects host cells from the...

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PMID: 8901518
DOI: 10.1021/bi960541u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-8901518-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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