Article
Cloning, sequencing and disruption of a bromoperoxidase-catalase gene in Streptomyces venezuelae: evidence that it is not required for chlorination in chloramphenicol biosynthesis.
Microbiology (Reading, England) - 1 Mar 1996
Facey Sandra J, Groß Frank, Vining Leo C, Yang Keqian, van Pé Karl-Heinz
Abstract excerpt
Genomic DNA libraries of Streptomyces venezuelae ISP5230 and of a mutant blocked at the chlorination step of chloramphenicol biosynthesis were probed by hybridization with a synthetic oligonucleotide corresponding to the N-terminal amino acid sequence of a bromoperoxidase-catalase purified from t...
Topics
- Amino Acid Sequence
- Base Sequence
- Chloramphenicol
- Cloning, Molecular
- DNA, Fungal
- Molecular Sequence Data
- Mutation
- Peroxidases
- Sequence Alignment
- Streptomyces