Article
High prevalence of serum apolipoprotein E4 isoprotein in rheumatoid arthritis patients with amyloidosis.
Arthritis and rheumatism - 1 Oct 1996
Hasegawa H, Nishi S, Ito S, Saeki T, Kuroda T, Kimura H, Watababe T, Nakano M, Gejyo F, Arakawa M
Abstract excerpt
OBJECTIVE: To determine whether serum Apolipoprotein E (Apo E) type 4 isoprotein is a risk factor for the development of amyloidosis in patients with rheumatoid arthritis (RA). METHODS: Using isoelectric focusing, we studied Apo E phenotype expression and the corresponding allele frequencies (epsilon 2, epsilon 3, and epsilon 4) in 35 patients with RA and amyloidosis, 65 patients with RA and without amyloidosis,...
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