Article
Von Wille-brand's disease in UK dobermanns: possible correlation of a polymorphic DNA marker with disease status.
The Journal of small animal practice - 1 Jul 1996
Holmes N G, Shaw S C, Dickens H F, Coombes L M, Ryder E J, Littlewood J D, Binns M M
Abstract excerpt
Ninety-one dobermanns have been typed for a polymorphic microsatellite DNA marker situated within an intron of the von Willebrand factor gene and the alleles correlated with von Wille-brand's disease status. Two alleles were identified, one associated only with the normal gene and the other with both normal and disease genes.
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