Article
DNA testing for type III von Willebrand disease in Dutch Kooiker dogs.
Journal of veterinary internal medicine - 1 Jan 2000
van Oost Bernard A, Versteeg Serge A, Slappendel Robbert J
Abstract excerpt
Von Willebrand disease type III is widespread in Dutch Kooiker dogs. To eradicate von Willebrand disease from the breed, affected dogs and nonsymptomatic carriers must be excluded from breeding. Previous efforts to detect carriers in Kooiker dogs by a von Willebrand factor antigen assay were not satisfactory because of considerable overlap of plasma concentrations in normal dogs and carriers. The aim of this...
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