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Article

Determination of a molecular map position for Hyp using a new interspecific backcross produced by in vitro fertilization.

Genomics - 1 Nov 1991

Kay G, Thakker R V, Rastan S

Abstract excerpt

We have established a Mus spretus/Mus musculus domesticus interspecific backcross segregating for two X-linked mutant genes, Ta and Hyp, using in vitro fertilization. The haplotype of the recombinant X chromosome of each of 241 backcross progeny has been established using the X-linked anchor loci Otc, Hprt, Dmd, Pgk-1, and Amg and the additional probes DXSmh43 and Cbx-rs1. The Hyp locus (putative homologue of the...

Topics

Alkaline Phosphatase
Animals
Blotting, Southern
Calcium
Chromosome Mapping
Crosses, Genetic
DNA Probes
Female
Fertilization in Vitro

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genetic Linkage

Humans

Hypophosphatemia, Familial

Male

Mice

Mutation

Phosphates

Polymorphism, Restriction Fragment Length

Recombination, Genetic

Source

Identifiers

PMID: 1685478
DOI: 10.1016/0888-7543(91)90072-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1685478-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Determination of a molecular map position for Hyp using a new interspecific backcross produced by in vitro fertilization.PMID 1685478Read ↗

Fine genetic mapping of the Hyp mutation on mouse chromosome X.Semantic proximity Read ↗

Multilocus mapping of the X-linked hypophosphatemic rickets gene.Semantic proximity Read ↗

Genetic mapping in the Xp11.2 region of a new form of X-linked hypophosphatemic rickets.Semantic proximity Read ↗

Sub-milliMorgan map of the proximal part of mouse Chromosome 17 including the hybrid sterility 1 gene.Semantic proximity Read ↗

Efficient linkage of 10 loci in the proximal region of the mouse X chromosome.Semantic proximity Read ↗

Molecular characterisation of the Hyp deletion and an improved assay for its detection.Semantic proximity Read ↗

The X chromosome deletion in HYP mice extends into the intergenic region but does not include the SAT gene downstream from Phex.Semantic proximity Read ↗

High-resolution comparative mapping of the proximal region of the mouse X chromosome.Semantic proximity Read ↗

An integrated genetic map of the pearl locus of mouse chromosome 13.Semantic proximity Read ↗

Meiotic crossover hotspots contained in haplotype block boundaries of the mouse genome.Semantic proximity Read ↗

The genetic map around the tail kinks (tk) locus on mouse chromosome 9.Semantic proximity Read ↗

Mapping a gene for familial situs abnormalities to human chromosome Xq24-q27.1.Semantic proximity Read ↗

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