Experimental study on cleft lip and/or palate: fetuses of A/J mice in uteri of F1 hybrid mothers using ovarian transplantation.

doi:10.1597/1545-1569_1996_033_0291_esocla_2.3.co_2

Article

Experimental study on cleft lip and/or palate: fetuses of A/J mice in uteri of F1 hybrid mothers using ovarian transplantation.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Jul 1996

Yoshida K, Natsume N, Kinoshita H, Tsunoda N, Takahashi H, Kawai T

Abstract excerpt

The A/J inbred strain of mice spontaneously develops cleft lip and/or palate (CL/P). Ovarian transplantation and several test-matings with C57BL/6 strain mice (0% CL/P) were performed to investigate a relationship between mother and fetus in regard to this order. The fetuses obtained showed that regardless of whether the genetic background of the mother was A/J or F1, CL/P was produced only in cases where the...

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