Article
Extended gene diversity at the FMR1 locus and neighbouring CA repeats in a sub-Saharan population.
American journal of medical genetics - 12 Jul 1996
Chiurazzi P, Destro-Bisol G, Genuardi M, Oostra B A, Spedini G, Neri G
Abstract excerpt
We report on the allele distributions in a normal black African population at two microsatellite loci neighbouring the FRAXA locus and at the CGG repeat in the 5' end of the FMR-1 gene, which causes the fragile X syndrome. The CGG repeat distribution was found to be similar to that of other ethnic groups, as well as to that of other nonhuman primates, possibly predicting a comparable prevalence of fragile X in...
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