Article
Survey of the fragile X syndrome CGG repeat and the short-tandem-repeat and single-nucleotide-polymorphism haplotypes in an African American population.
American journal of human genetics - 1 Feb 2000
Crawford D C, Schwartz C E, Meadows K L, Newman J L, Taft L F, Gunter C, Brown W T, Carpenter N J, Howard-Peebles P N, Monaghan K G, Nolin S L, Reiss A L, Feldman G L, Rohlfs E M, Warren S T, Sherman S L
Abstract excerpt
Previous studies have shown that specific short-tandem-repeat (STR) and single-nucleotide-polymorphism (SNP)-based haplotypes within and among unaffected and fragile X white populations are found to be associated with specific CGG-repeat patterns. It has been hypothesized that these associations result from different mutational mechanisms, possibly influenced by the CGG structure and/or cis-acting factors....
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