Allele frequencies in a worldwide survey of a CA repeat in the first intron of the CFTR gene.

doi:10.1159/000022834

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Article

Allele frequencies in a worldwide survey of a CA repeat in the first intron of the CFTR gene.

Human heredity - 1 Jan 1999

Mateu E, Calafell F, Bonné-Tamir B, Kidd J R, Casals T, Kidd K K, Bertranpetit J

Abstract excerpt

A dinucleotide CA repeat within intron 1 of the CFTR gene has recently been identified. We have determined the allele frequencies of this polymorphism in samples from 18 populations covering all major geographical areas, with a total of 1,816 chromosomes. When considering allele distributions, Af...

Topics

Alleles
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Dinucleotide Repeats
Gene Frequency
Genetics, Population
Humans
Introns
Polymorphism, Genetic
Tandem Repeat Sequences

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