Article
The Cbp2 protein suppresses splice site mutations in a group I intron.
Nucleic acids research - 1 Sept 1996
Shaw L C, Thomas J, Lewin A S
Abstract excerpt
The Cbp2 protein facilitates the folding of a group I intron in the COB pre-mRNA of yeast mitochondria. Based on its ability to suppress mutations affecting the auto-catalytic reaction, the protein appears to play a role in the selection of splice sites. Adding Cbp2 did not overcome the effects of mutations in P1 whose primary effect was on the first step of splicing. In contrast, most mutations affecting the...
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