Article
Androgen insensitivity syndrome due to new mutations in the DNA-binding domain of the androgen receptor.
Molecular and cellular endocrinology - 18 Jun 1996
Imasaki K, Okabe T, Murakami H, Tanaka Y, Haji M, Takayanagi R, Nawata H
Abstract excerpt
Androgen insensitivity syndrome (AIS) is associated with a wide range of quantitative or qualitative defects in the androgen receptor (AR). In some patients with AIS, however, no defects are detectable in the ligand-binding properties of the AR. We have analyzed the ARs of two unrelated patients with this category (termed 'receptor-positive type') of AIS. Sequence analysis of these patients' AR gene revealed...
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